The Complete Guide to NAD+ Supplements
NAD+, also known as nicotinamide adenine dinucleotide, is a component that is vital to over 200
metabolic processes. It has a crucial role in energy production, DNA repair, gene expression, immune
system health, nutrient signaling and function, and many other processes.
NAD+ is essential for health and longevity. As we age and our cells are exposed to more damage,
however, NAD+ concentrations wane. The state of low NAD+ levels is sometimes called NAD+
deficiency.
You can boost your NAD+ levels naturally somewhat, but natural methods of boosting NAD+ are best
as preventative measures. The most effective way to raise and maintain NAD+ levels in bodies where
NAD+ levels are already depleted is through supplementation.
Learn more about NAD+ deficiency and NAD+ science.
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NAD+ supplements are external sources of NAD+ and components that make NAD+ (called NAD+
precursors). They usually contain niacin (vitamin B3), nicotinamide, nicotinamide riboside,
nicotinamide mononucleotide, and pure NAD+. When pure NAD+ is contained in the supplement,
the pieces of NAD+ will be broken apart and put back together inside the cells.
Most NAD+ supplements only contain NAD+ or a NAD+ precursor and some vehicle of delivery that
isn't an active ingredient. For NAD+ delivered through an IV, for example, the active ingredient
should only be accompanied by sterile water.
Supplements that can be taken at home, like pills, sublingual tablets, or patches, usually only contain
NAD+ or NAD+ precursors as the active ingredient. Any other components or active ingredients
should be listed on the label.
There are numerous reasons why you might want to supplement with NAD+. NAD+ makes it possible
for cells to carry out the hundreds of jobs they are responsible for. NAD+ concentration naturally
reduces as we age; simultaneously, as our cells become debilitated, they need more NAD+ to repair
and protect cell function.
NAD+ concentrations can somewhat improve with diet and exercise, but the improvement is often
minimal, especially if NAD+ concentrations are already deficient. NAD+ supplementation therapy can
help to recuperate NAD+ in the cells in a short amount of time. Some of the research-backed
benefits include:
- Protecting against a decline in artery and vein function
- Repairing DNA
- Aiding in addiction therapies
- Supporting over 200 functions throughout the body
- Improvements in energy
- Reduced risk of age-related diseases.
Learn more about the benefits of NAD supplementation therapy and about choosing the right NAD+
supplement for you.
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Numerous supplements help to increase NAD+ concentrations. The most common components
found in NAD+ supplements have niacin (vitamin B3), nicotinamide, nicotinamide riboside,
nicotinamide mononucleotide, and pure NAD+.
In addition to the components, it is also essential to consider the form of delivery. The most
common forms of at-home NAD+ delivery include an oral pill, NAD+ patches, and NAD+ sublingual
tablets. You can also get injections and IVs with NAD+ for more intensive treatments, but these are
only administered in specialized facilities.
When it comes to the patch form of the NAD+ supplement 1000mg is the most common and the
most effective. You change the patch monthly, and NAD+ is released slowly over the course of the
month. As for the NAD sublingual tablets, these most effective form is in NAD+ 100mg sublingual
losenges.
The Longevity Collective offers both sublingual tablets and patches as one-time-purchase or as a
monthly subscription.
- 100mg NAD+ sublingual tablets (losenges)
- 100 mg NAD+ sublingual tablets (losenges) monthly subscription
- NAD+ supplement 1000mg patches
- NAD supplement 1000mg patches monthly subscription
- See all NAD+ supplement products
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NAD+ 1000mg supplements are steady-release supplements in patch form. The patch, which may
look like a simple sticker, actually uses an innovative technology called Transdermal Drug Delivery
(TDD).
The 1000mg of NAD+ within the patch is released slowly through the skin (technically, it passes
through the stratum corneum, then through the deeper epidermis and dermis) into the
bloodstream.
The advantages of 1000mg NAD+ patches are that it is released slowly directly to the bloodstream,
and the blood takes it to where it is most needed. Because of this, there is no NAD+ accumulation in
one area of the body or removal by the body due to high doses. Additionally, people who choose to
use the patches get a steady release of NAD+ for the entire month of use. This is beneficial for
people who frequently forget to take pills and losenges. Instead, it is replaced only once a month.
So you don't go a day without your NAD+ supplements, you can get an automatic monthly
subscription of NAD+ 1000mg patches delivered right to your door.
Learn more about NAD+ patches for health and wellness.
There are hundreds of thousands of products out there that promise to improve your health and
wellness. However, few products have an active ingredient with the robust research to demonstrate
its role in supporting health, as does NAD+. Long before NAD+ supplementation was even an option,
NAD+ had been identified as a vital component to life and health. When scientists found ways to
increase NAD+ concentrations in human cells through supplementation, it was a game-changer.
NAD+ patches use the latest and greatest technology to provide your cells with the components they
need to build NAD+ while also making it as easy as possible for you at home without worrying about
medical costs, forgetfulness, and a lack of convenience. They are wearable NAD+ supplements that
provide your body with a steady dosage of NAD+ over several hours of wearing it.
The ways NAD+ patched support health and wellness include:
- Helping cells to fight against unhealthy aging
- Protecting brain cell function
- Potentially lowering the risk of heart disease
- Potentially lowering cancer risk
- Supporting muscle function as you age
- Helping to regulate the body's circadian rhythms
Learn more about how NAD+ patches support health and wellness.
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NAD+ sublingual tablets, also called NAD+ losenges, are another form of NAD+ supplementation that
is highly effective.
The skin under the tongue allows for direct passage of microscopic components into the
bloodstream without the degradation supplements can endure when going through the digestive
system. Instead, when the losenges are placed under the tongue, they are absorbed quickly and
efficiently into the bloodstream and then to the cells for use.
The benefit of sublingual losenges is that they increase the retention time of the dosage by way of
the oral cavity. This increases bioavailability, reduces gastric irritation, and bypasses first-pass
metabolism, a normal process in the body that reduces the availability of a component for use.
Learn more about the sublingual losenges here.
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Thankfully, there are plenty of options when it comes to NAD supplements.
Some of the things to consider include:
- Your current NAD+ levels. Very low NAD+ levels or therapeutic NAD+ for addictions may call
for medical NAD+ intervention, including an injection of NAD+ or intravenous NAD+. If your
NAD+ levels are depleting, or you want to prevent the effects of aging, some at-home
options, like sublingual tablets and transdermal patches may be enough.
- Your lifestyle. If you are someone who likes routine and rarely forgets things, you may
benefit from sublingual tablets. If you are a forgetful person or simply down want another
thing to think about, transdermal patches can deliver the NAD+ to your cells slowly over
several hours.
- Your preferences. For different reasons, including what you are used to and cost, you may
prefer one supplement over another.
- What your doctor says. Your NAD+-informed physician can help you decide on the best
NAD+ supplement form for you based on your medical history, health condition, and
preferences.
Learn more about how to select the right NAD supplements for your health.
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